(±)17-HETE (Synonyms: (±)-Hydroxyeicosatetraenoic Acid) |
| Katalog-Nr.GC40435 |
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
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Cas No.: 128914-47-6
Sample solution is provided at 25 µL, 10mM.
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Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 µM the (S)-enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R)-isomer is inactive.
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