2′-O-Methylcytidine |
| Katalog-Nr.GC48873 |
&2#8242;-O-Methylcytidin ist ein 2'-substituiertes Nukleosid als Inhibitor der HCV-Replikation.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2140-72-9
Sample solution is provided at 25 µL, 10mM.
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2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50 = 3.8 µM).1 It inhibits HCV replication in a replicon assay (IC50 = 21.2 µM).
1.Migliaccio, G., Tomassini, J.E., Carroll, S.S., et al.Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitroJ. Bio. Chem.278(49)49164-49170(2003)
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