Nifekalant (hydrochloride) (Synonyms: MS-551) |
| Katalog-Nr.GC44403 |
Nifekalant (Hydrochlorid) (MS-551), ein Antiarrhythmikum der Klasse III, ist ein IKr-Kaliumkanalblocker mit einer IC50 von 10 µM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 130656-51-8
Sample solution is provided at 25 µL, 10mM.
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Nifekalant is a class III antiarrhythmic agent that has been shown to be beneficial to initial resuscitation after cardiac arrest in clinical trials. It blocks the rapidly activating delayed rectifier potassium channel (IKr; IC50 = 10 µM). Nifekalant is also inhibits the human multidrug and toxin extrusion (MATE) transporter 1 (MATE1; IC50 = 6.5 µM).
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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