3',4'-Dihydroxyflavonol |
| Katalog-Nr.GC34451 |
3',4'-Dihydroxyflavonol (DiOHF) ist ein wirksames Antioxidans, das Superoxid reduziert und die Stickoxid (NO)-Funktion in diabetischen RattengekrÖsearterien verbessert.
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Cas No.: 6068-78-6
Sample solution is provided at 25 µL, 10mM.
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3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) function in diabetic rat mesenteric arteries[1].
3',4'-Dihydroxyflavonol (DiOHF) acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling to improve endothelial function[1].3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²? desensitization in permeabilized third-order branches of rat mesenteric arteries[2].
[1]. Leo CH, et al. 3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries. PLoS One. 2011;6(6):e20813. [2]. Kim HY, et al. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²? desensitization in permeabilized rat mesenteric artery. Naunyn Schmiedebergs Arch Pharmacol. 2012 Feb;385(2):191-202.
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