AG 205 |
| Katalog-Nr.GC50394 |
Progesterone receptor membrane component 1 (Pgrmc1) ligand
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Progesterone receptor membrane component 1 (Pgrmc1) ligand. Inhibits cell cycle progression and cell viability in cancer cell lines. Inhibits progesterone induced cytosolic Ca2+ increases in GnRH neurons in vitro.
Ahmed et al (2010) Progesterone receptor membrane component 1 (Pgrmc1): a heme-1 domain protein that promotes tumorigenesis and is inhibited by a small molecule. J.Pharmacol.Exp.Ther. 333 564 PMID:20164297 |Bashour and Wray (2012) Progesterone directly and rapidly inhibits GnRH neuronal activity via progesterone receptor membrane component 1. Endocrinology. 153 4457 PMID:22822163 |Yoshitani et al (2005) A structure-based strategy for discovery of small ligands binding to functionally unknown proteins: combination of in silico screening and surface plasmon resonance measurements. Proteomics. 5 1472 PMID:15798990
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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