Amastatin (hydrochloride) |
| Katalog-Nr.GC42777 |
Amastatin (Hydrochlorid) ist ein langsamer, stark bindender, kompetitiver Aminopeptidase (AP)-Inhibitor mit Ki-Werten von 0,26 nM, 30 nM, 52 nM für Aeromonas-Aminopeptidase, zytosolische Leucin-Aminopeptidase, mikrosomale Aminopeptidase.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 100938-10-1
Sample solution is provided at 25 µL, 10mM.
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Amastatin is a slow, tight binding, competitive aminopeptidase (AP) inhibitor, first described as an inhibitor of human serum AP-A (glutamyl AP; IC50 = 0.54 µg/ml) but not of AP-B (arginine AP). It also inhibits AP-N (AP-M, alanyl AP; Ki = 20-200 nM), leucyl-cystinyl AP (Ki = 20-220 nM), and endoplasmic reticulum AP 1 (Ki = 41.8 µM). Amastatin is without effect on trypsin, papain, chymotrypsin, elastase, pepsin, or thermolysin.
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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