Apcin-A |
Katalog-Nr.GC62419 |
Apcin-A, ein Apcin-Derivat, ist ein Inhibitor des Anaphase-fÖrdernden Komplexes (APC). Apcin-A interagiert stark mit Cdc20 und hemmt die Ubiquitinierung von Cdc20-Substraten. Apcin-A kann verwendet werden, um das PROTAC CP5V zu synthetisieren.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1683617-62-0
Sample solution is provided at 25 µL, 10mM.
Apcin-A, an Apcin derivative, is an anaphase-promoting complex (APC) inhibitor. Apcin-A interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V [1].
[1]. Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.
Average Rating: 5
(Based on Reviews and 1 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *