Biotinylated-JQ1 (Synonyms: Biotin-JQ1) |
| Katalog-Nr.GC64789 |
Biotinyliertes JQ1 (Biotin-JQ1) ist ein biotinyliertes Derivat von JQ1 mit hoher AffinitÄt fÜr die BromodomÄne von BRD4. Biotinyliertes JQ1 hemmt die Proliferation von multiplen MM1.S-Myelomzellen mit einem EC50-Wert von 0,4μM.
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Cas No.: 1635437-52-3
Sample solution is provided at 25 µL, 10mM.
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Biotinylated-JQ1 (Biotin-JQ1) is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM[1].
Biotinylated-JQ1 (0.1 nM-100 μM; 72 hours) inhibits MM1.S cell proliferation with an EC50 of 0.4 μM[1].
[1]. Lars Anders, et al. Genome-wide localization of small molecules. Nat Biotechnol. 2014 Jan;32(1):92-6.
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