Bz-RS-iSer(3-Ph)-OMe |
Katalog-Nr.GC39739 |
Bz-RS-iSer(3-Ph)-OMe (Verbindung 2), ein Taxol-Derivat, hemmt den HSV-Replikationszyklus bei geringer ZytotoxizitÄt, blockiert die mitotische Teilung von Vero-Zellen, beeinflusst die M-MSV-induzierte TumorgrÖße und beeinflusst die Immunantwort durch Hemmung von PHA -induzierte T-Lymphozyten-Proliferation.
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Cas No.: 32981-85-4
Sample solution is provided at 25 µL, 10mM.
Bz-RS-iSer(3-Ph)-OMe (compound 2), a Taxol derivative, inhibits HSV replication cycle at low cytotoxicity, blocks mitotic divisions of Vero cells, influences M-MSV induced tumor size and affects immune response by inhibiting PHA-induced T lymphocyte proliferation[1].
[1]. Krawczyk E, et al. Cytotoxic, antiviral (in-vitro and in-vivo), immunomodulatory activity and influence on mitotic divisions of three taxol derivatives: 10-deacetyl-baccatin III, methyl (N-benzoyl-(2'R,3'S)-3'-phenylisoserinate) and N-benzoyl-(2'R,3'S)-3'-phenylisoserine. J Pharm Pharmacol. 2005;57(6):791‐797.
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