15(S)-HETE-d8 (Synonyms: 15(S)-Hydroxyeicosatetraenoic Acid-d8)

Name: 15(S)-HETE-d8
Brand: GlpBio
SKU: GC46442
Availability: InStock
Rating: 5 (31 reviews)

Katalog-Nr.GC46442

An internal standard for the quantification of 15-HETE

Products are for research use only. Not for human use. We do not sell to patients.

15(S)-HETE-d8 Chemische Struktur

Cas No.: 84807-87-4

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25 μg	248,00 $	Auf Lager
50 μg	473,00 $	Auf Lager
100 μg	894,00 $	Auf Lager

Tel：(909) 407-4943 Email: sales@glpbio.com

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Basiert auf Kundenrezensionen.

Sample solution is provided at 25 µL, 10mM.

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Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

View current batch:

Purity: >99.00%

15(S)-HETE-d₈ contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 15(S)-HETE by GC- or LC-MS. 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.¹ 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.²

1.Nadel, J.A., Conrad, D.J., Ueki, I.F., et al.Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocyes, leukocytes, and airway cellsJournal of Clinical Investigation871139-1145(1991) 2.Ramis, I., RosellÓ-Catafau, J., Bulbena, O., et al.15-Hydroxyeicosatetraenoic acid as a major eicosanoid in nasal secretions: Assay by high-performance liquid chromatographic-radioimmunoassay and gas chromatographic-mass spectrometric proceduresJournal of Chromatography496416-422(1989)

Cas No.	84807-87-4	SDF
Überlieferungen	15(S)-Hydroxyeicosatetraenoic Acid-d8
Canonical SMILES	CCCCC[C@]([2H])(O)/C([2H])=C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCC(O)=O
Formula	C20H24D8O3	M.Wt	328.5
Löslichkeit	0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS pH 7.2: 0.8 mg/ml	Storage	Store at -20°C
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
		1 mg	5 mg	10 mg
	1 mM	3.0441 mL	15.2207 mL	30.4414 mL
	5 mM	0.6088 mL	3.0441 mL	6.0883 mL
	10 mM	0.3044 mL	1.5221 mL	3.0441 mL

Molaritätsrechner
Verdünnung-Rechner

Berechnen

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal:μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 31 reference(s) in Google Scholar.)

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15(S)-HETE-d8 (Synonyms: 15(S)-Hydroxyeicosatetraenoic Acid-d8)

Kundenbewertungen

GlpBio Citations

Bioactive Compounds Premium Provider

GlpBio Produkte in seriösen Veröffentlichungen zitiert

Product Documents

Quality Control & SDS

Complete Stock Solution Preparation Table

Molaritätsrechner

Verdünnung-Rechner

In vivo Formulation Calculator (Clear solution)

Bewertungen