Carviolin |
| Katalog-Nr.GC47046 |
Carviolin ist eine Verbindung, die aus dem Mycel des Schlauchpilzes Neobulgaria pura isoliert wird.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 478-35-3
Sample solution is provided at 25 µL, 10mM.
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Carviolin is an anthraquinone fungal metabolite that has been found in Z. longicaudata with immunosuppressive and antitrypanosomal activities.1,2 It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes (IC50s = 4 and 4.5 µg/ml, respectively).1 Carviolin is active against T. b. brucei (MIC = 41.66 µM).2
1.Fujimoto, H., Nakamura, E., Okuyama, E., et al.Six immunosuppressive features from an ascomycete, Zopfiella longicaudata, found in a screening study monitored by immunomodulatory activityChem. Pharm. Bull. (Tokyo)52(8)1005-1008(2004) 2.Aly, A.H., Debbab, A., Clements, C.M., et al.NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorumBioorg. Med. Chem.19(1)414-421(2011)
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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