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Innate Immunity

Produkte für  Innate Immunity

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  2. GC45206 α-GalCer analog 8

    α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.

    α-GalCer analog 8  Chemical Structure
  3. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) α-MSH (α-Melanozyten-stimulierendes Hormon) TFA, ein endogenes Neuropeptid, ist ein endogener Melanocortinrezeptor 4 (MC4R)-Agonist mit entzÜndungshemmenden und antipyretischen AktivitÄten. α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)  Chemical Structure
  4. GC41499 α-Phellandrene α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities. α-Phellandrene  Chemical Structure
  5. GC48920 β-Carboline-1-carboxylic Acid An alkaloid with diverse biological activities β-Carboline-1-carboxylic Acid  Chemical Structure
  6. GC48298 β-Defensin-2 (human) (trifluoroacetate salt) An antimicrobial peptide β-Defensin-2 (human) (trifluoroacetate salt)  Chemical Structure
  7. GC45230 β-Defensin-3 (human) (trifluoroacetate salt) β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. β-Defensin-3 (human) (trifluoroacetate salt)  Chemical Structure
  8. GC45231 β-Defensin-4 (human) (trifluoroacetate salt) β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. β-Defensin-4 (human) (trifluoroacetate salt)  Chemical Structure
  9. GC52010 (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid An oxylipin gut microbiota metabolite (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid  Chemical Structure
  10. GC40466 (±)11(12)-EET (±)11(12)-EET ist ein NLRP3-Inflammasom-Inhibitor. (±)11(12)-EET  Chemical Structure
  11. GC40802 (±)12(13)-DiHOME

    (±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.

    (±)12(13)-DiHOME  Chemical Structure
  12. GC41288 (±)17(18)-EpETE-Ethanolamide (±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide. (±)17(18)-EpETE-Ethanolamide  Chemical Structure
  13. GC40362 (±)18-HEPE (±)18-HEPE is produced by non-enzymatic oxidation of EPA. (±)18-HEPE  Chemical Structure
  14. GC41655 (±)19(20)-EDP Ethanolamide (±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). (±)19(20)-EDP Ethanolamide  Chemical Structure
  15. GC40801 (±)9(10)-DiHOME (±)9(10)-DiHOME ist das Racemat von 9,10-DiHOME. (±)9(10)-DiHOME  Chemical Structure
  16. GC45272 (-)-Rasfonin (-)-Rasfonin ist ein Pilz-SekundÄrmetabolit und hemmt kleine G-Proteine Ras. (-)-Rasfonin induziert Apoptose, Nekrose und Autophagie in ACHN-Zellen (einer Nierenkarzinom-Zelllinie). (-)-Rasfonin  Chemical Structure
  17. GC41712 (R)-3-hydroxy Myristic Acid Lipopolysaccharides (LPS) are components of the cell walls of Gram-negative bacteria. (R)-3-hydroxy Myristic Acid  Chemical Structure
  18. GC46352 (S)-DO271 An inactive control for DO264 (S)-DO271  Chemical Structure
  19. GC41740 (S)-p38 MAPK Inhibitor III (S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). (S)-p38 MAPK Inhibitor III  Chemical Structure
  20. GC49768 1,1’-Ethylidene-bis-(L-tryptophan) A potential impurity found in commercial preparations of L-tryptophan 1,1’-Ethylidene-bis-(L-tryptophan)  Chemical Structure
  21. GC41855 1,3-Distearoyl-2-Oleoyl-rac-glycerol 1,3-Distearoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position. 1,3-Distearoyl-2-Oleoyl-rac-glycerol  Chemical Structure
  22. GC49294 1-(4-Chlorobenzhydryl)piperazine An inactive metabolite of meclizine and chlorcyclizine 1-(4-Chlorobenzhydryl)piperazine  Chemical Structure
  23. GC41986 1-Arachidonoyl Lysophosphatidic Acid (ammonium salt)

    1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position.

    1-Arachidonoyl Lysophosphatidic Acid (ammonium salt)  Chemical Structure
  24. GC52186 1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC 1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC  Chemical Structure
  25. GC46481 1-Hydroxyphenazine A P. aeruginosa virulence factor 1-Hydroxyphenazine  Chemical Structure
  26. GC41998 1-Methyl-4-imidazoleacetic Acid (hydrochloride) 1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine. 1-Methyl-4-imidazoleacetic Acid (hydrochloride)  Chemical Structure
  27. GC40910 1-Oleoyl-2-hydroxy-sn-glycero-3-PE 1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. 1-Oleoyl-2-hydroxy-sn-glycero-3-PE  Chemical Structure
  28. GC42026 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC ist ein hÄufig vorkommendes Gonaden-LPC (Lysophosphatidylcholin). 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC  Chemical Structure
  29. GC42035 1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol 1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains palmitic, stearic, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. 1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol  Chemical Structure
  30. GC45693 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC  Chemical Structure
  31. GC49730 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11  Chemical Structure
  32. GC41331 1-Stearoyl-2-hydroxy-sn-glycero-3-PC 1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated 18:0 lysophosphatidylcholine found in plasma and oxidized LDL that is thought to play a role in inflammatory diseases and atherosclerosis. 1-Stearoyl-2-hydroxy-sn-glycero-3-PC  Chemical Structure
  33. GC46498 1-Stearoyl-d35-2-hydroxy-sn-glycero-3-PC An internal standard for the quantification of 1-stearoyl-2-hydroxy-sn-glycero-3-PC 1-Stearoyl-d35-2-hydroxy-sn-glycero-3-PC  Chemical Structure
  34. GC40971 10(S),17(S)-DiHDHA 10(S),17(S)-DiHDHA (auch als Neuroprotectin D1 bekannt, wenn es in neuronalen Geweben produziert wird) ist eine von DHA abgeleitete DihydroxyfettsÄure, die starke schÜtzende und entzÜndungshemmende AktivitÄten aufweist. 10(S),17(S)-DiHDHA  Chemical Structure
  35. GC41875 11(Z),14(Z)-Eicosadienoic Acid methyl ester 11(Z),14(Z)-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic Acid methyl ester  Chemical Structure
  36. GC41144 11-trans Leukotriene C4 11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. 11-trans Leukotriene C4  Chemical Structure
  37. GC52343 113-O12B An ionizable cationic lipidoid 113-O12B  Chemical Structure
  38. GC18637 11β-Prostaglandin F2α

    11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.

    11β-Prostaglandin F2α  Chemical Structure
  39. GC40447 12(R)-HETE Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid. 12(R)-HETE  Chemical Structure
  40. GC41123 12-epi Leukotriene B4 Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. 12-epi Leukotriene B4  Chemical Structure
  41. GC41096 12-oxo Leukotriene B4 Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. 12-oxo Leukotriene B4  Chemical Structure
  42. GC49912 13C20,15N10-Cyclic di-GMP (sodium salt) An internal standard for the quantification of cyclic di-GMP 13C20,15N10-Cyclic di-GMP (sodium salt)  Chemical Structure
  43. GC41100 14,15-dehydro Leukotriene B4 Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. 14,15-dehydro Leukotriene B4  Chemical Structure
  44. GC41145 14,15-Leukotriene C4 Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. 14,15-Leukotriene C4  Chemical Structure
  45. GC41148 14,15-Leukotriene D4 14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. 14,15-Leukotriene D4  Chemical Structure
  46. GC41150 14,15-Leukotriene E4 Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. 14,15-Leukotriene E4  Chemical Structure
  47. GC41164 15(R)-15-methyl Prostaglandin D2 15(R)-15-methyl Prostaglandin D2 (15(R)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2. 15(R)-15-methyl Prostaglandin D2  Chemical Structure
  48. GC41415 15(R)-Lipoxin A4

    Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function.

    15(R)-Lipoxin A4  Chemical Structure
  49. GC40451 15(S)-HETE 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE  Chemical Structure
  50. GC49178 17(R)-Protectin D1 An aspirin-triggered epimer of protectin D1 17(R)-Protectin D1  Chemical Structure
  51. GC41951 17(R)-Resolvin D1

    Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.

    17(R)-Resolvin D1  Chemical Structure
  52. GC41227 17(R)-Resolvin D1 methyl ester 17(R)-Resolvin D1 (17(R)-RvD1) is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with equipotency to RvD1 (EC50 = ~30 nM). 17(R)-Resolvin D1 methyl ester  Chemical Structure
  53. GC45307 17(R)-Resolvin D3   17(R)-Resolvin D3  Chemical Structure
  54. GC41208 17(S)-HDHA 17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain. 17(S)-HDHA  Chemical Structure
  55. GC40975 17(S)-HpDHA 17(S)-HpDHA is a mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, human glial cells, and mouse brain. 17(S)-HpDHA  Chemical Structure
  56. GC41160 1a,1b-dihomo Prostaglandin E2 1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid. 1a,1b-dihomo Prostaglandin E2  Chemical Structure
  57. GC42080 2'2'-cGAMP (sodium salt) 2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. 2'2'-cGAMP (sodium salt)  Chemical Structure
  58. GC42123 2-Aminopurine (hydrochloride) 2-Aminopurin (Hydrochlorid) ist ein fluoreszierendes Analogon von Guanosin. 2-Aminopurine (hydrochloride)  Chemical Structure
  59. GC42135 2-chloro Palmitic Acid 2-ChlorpalmitinsÄure, ein entzÜndlicher Lipidmediator, stÖrt die Proteinpalmitylierung, induziert ER-Stressmarker, reduziert den ER-ATP-Gehalt und aktiviert die Transkription und Sekretion von IL-6 sowie IL-8.2-ChlorpalmitinsÄure stÖrt die Mitochondrien Membranpotential und induziert die Procaspase-3- und PARP-Spaltung. 2-ChlorpalmitinsÄure kann die Blut-Hirn-Schranke (BBB) Überwinden und beeintrÄchtigt ER- und Mitochondrienfunktionen in der Endothelzelllinie hCMEC/D3 des menschlichen Gehirns. 2-chloro Palmitic Acid  Chemical Structure
  60. GC42136 2-chloro Stearic Acid 2-chloro Stearic acid is a bioactive fatty acid that accumulates in primary human monocytes and neutrophils as well as murine neutrophils stimulated with phorbol 12-myristate 13-acetate. 2-chloro Stearic Acid  Chemical Structure
  61. GC42082 20-carboxy Leukotriene B4 20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. 20-carboxy Leukotriene B4  Chemical Structure
  62. GC41421 20-hydroxy Leukotriene B4 20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. 20-hydroxy Leukotriene B4  Chemical Structure
  63. GC40571 24(S),25-epoxy Cholesterol

    24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.

    24(S),25-epoxy Cholesterol  Chemical Structure
  64. GC48482 28-Acetylbetulin A lupane triterpenoid with anti-inflammatory and anticancer activities 28-Acetylbetulin  Chemical Structure
  65. GC49122 3′-deoxy Thymidine An antiviral nucleoside analog 3′-deoxy Thymidine  Chemical Structure
  66. GC42242 3'-sulfo Galactosylsphingosine (ammonium salt) 3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. 3'-sulfo Galactosylsphingosine (ammonium salt)  Chemical Structure
  67. GC46583 3-Amino-2,6-Piperidinedione An active metabolite of (±)-thalidomide 3-Amino-2,6-Piperidinedione  Chemical Structure
  68. GC45354 4β-Hydroxywithanolide E 4β-Hydroxywithanolide E, isoliert aus Physalis peruviana L. 4β-Hydroxywithanolide E  Chemical Structure
  69. GC42338 4-Aminobenzoic Acid hydrazide 4-AminobenzoesÄurehydrazid ist ein irreversibler MPO-Myeloperoxidase-Hemmer mit einem IC50-Wert von 0,3 μM. 4-Aminobenzoic Acid hydrazide  Chemical Structure
  70. GC46630 4-CPPC A MIF-2 inhibitor 4-CPPC  Chemical Structure
  71. GC42369 4-Deoxypyridoxine (hydrochloride) 4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities. 4-Deoxypyridoxine (hydrochloride)  Chemical Structure
  72. GC42374 4-epi-Chlortetracycline (hydrochloride) Chlortetracycline is an analog of tetracycline, a broad spectrum antibiotic. 4-epi-Chlortetracycline (hydrochloride)  Chemical Structure
  73. GA20418 4-Hydroxy-hippuric acid Polyphenol metabolite. 4-Hydroxy-hippuric acid  Chemical Structure
  74. GC46673 4-octynyl Itaconate 4-Octinyl-Itaconat (ITalk) ist eine spezifische bioorthogonale Sonde fÜr die quantitative und ortsspezifische chemoproteomische Profilierung von Itaconation in lebenden Zellen. 4-octynyl Itaconate  Chemical Structure
  75. GC48381 5'-pApA (sodium salt) A linearized form of cyclic di-AMP 5'-pApA (sodium salt)  Chemical Structure
  76. GC48375 5'-pGpG (sodium salt) A linearized form of cyclic di-GMP 5'-pGpG (sodium salt)  Chemical Structure
  77. GC41126 5(S),12(S)-DiHETE 5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid. 5(S),12(S)-DiHETE  Chemical Structure
  78. GC41127 5(S),15(S)-DiHETE 5(S),15(S)-DiHETE ist ein „aktiviertes“ Intermediat, hemmt die Thrombozytenaggregation mit einem IC50 von 1,3 μM. 5(S),15(S)-DiHETE  Chemical Structure
  79. GC49827 5-Androstenetriol An active metabolite of DHEA 5-Androstenetriol  Chemical Structure
  80. GC45357 5-Chlorouracil   5-Chlorouracil  Chemical Structure
  81. GC40380 5-OxoETE

    5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase.

    5-OxoETE  Chemical Structure
  82. GC49676 6β-hydroxy Budesonide A metabolite of budesonide 6β-hydroxy Budesonide  Chemical Structure
  83. GC45772 6(5H)-Phenanthridinone An inhibitor of PARP1 and 2 6(5H)-Phenanthridinone  Chemical Structure
  84. GC40202 7α-hydroxy Cholesterol-d7

    7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.

    7α-hydroxy Cholesterol-d7  Chemical Structure
  85. GC46241 7-keto Cholesterol-d7

    7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL

    7-keto Cholesterol-d7  Chemical Structure
  86. GC48880 7-Methoxyflavone 7-Methoxyflavon ist eine aus Zornia brasiliensis isolierte Verbindung. 7-Methoxyflavone  Chemical Structure
  87. GC41136 8(S),15(S)-DiHETE 8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO. 8(S),15(S)-DiHETE  Chemical Structure
  88. GC42623 8-Bromoguanosine 8-Bromoguanosine is a brominated derivative of guanosine. 8-Bromoguanosine  Chemical Structure
  89. GC46748 9(E),11(E)-12-nitro Conjugated Linoleic Acid A nitrated fatty acid 9(E),11(E)-12-nitro Conjugated Linoleic Acid  Chemical Structure
  90. GC46749 9(E),11(E)-9-nitro Conjugated Linoleic Acid A nitrated fatty acid 9(E),11(E)-9-nitro Conjugated Linoleic Acid  Chemical Structure
  91. GC46757 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) An isomer of linoleic acid 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)  Chemical Structure
  92. GC49238 93-O17S A cationic lipidoid 93-O17S  Chemical Structure
  93. GC45960 9c(i472) 9c(i472) ist ein potenter Inhibitor von 15-LOX-1 (15-Lipoxygenase-1) mit einem IC50-Wert von 0,19 μM. 9c(i472)  Chemical Structure
  94. GC42683 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1). Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp  Chemical Structure
  95. GC52499 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt) A sensitive substrate for neutrophil elastase Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt)  Chemical Structure
  96. GC42684 Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1). Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt)  Chemical Structure
  97. GC42685 Ac-ANW-AMC Ac-ANW-AMC ist ein fluorogenes Substrat fÜr Immunoproteasom. Ac-ANW-AMC  Chemical Structure
  98. GC49704 Ac-FLTD-CMK (trifluoroacetate salt) An inhibitor of caspase-1, -4, -5, and -11 Ac-FLTD-CMK (trifluoroacetate salt)  Chemical Structure
  99. GC49263 Ac2-26 (human) (ammonium salt) An annexin A1-mimetic peptide Ac2-26 (human) (ammonium salt)  Chemical Structure
  100. GC46798 Adapalene-d3 An internal standard for the quantification of adapalene Adapalene-d3  Chemical Structure
  101. GC42763 Alamethicin F50 Alamethicin F50 is a peptaibol isolated from Trichoderma. Alamethicin F50  Chemical Structure

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