Betulin 3,28-diacetate (Synonyms: Betulin Diacetate, NSC 38876) |
| Katalog-Nr.GC48446 |
A triterpene with antiviral and hepatoprotective activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1721-69-3
Sample solution is provided at 25 µL, 10mM.
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Betulin 3,28-diacetate is a triterpene and derivative of betulin that has been found in B. pendula and has antiviral and hepatoprotective activities.1,2,3 It inhibits Semliki Forest virus (SFV) replication in virus-infected Huh7 cells (IC50 = 9.1 µM).2 Betulin 3,28-diacetate (20 mg/kg) increases the rate of bile secretion, a marker of hepatic function, in rat models of hepatitis induced by carbon tetrachloride, ethanol, or tetracycline .3
1.Salah, A., and Bakibaev, A.Effective method of extraction of betulin diacetate from birch barkJ. Nat. Prod. Resour.3(1)90-93(2017) 2.Pohjala, L., Alakurtti, S., Ahola, T., et al.Betulin-derived compounds as inhibitors of alphavirus replicationJ. Nat. Prod.72(11)1917-1926(2009) 3.Flekhter, O.B., Karachurina, L.T., Poroikov, V.V., et al.The synthesis and hepatoprotective activity of esters of the lupane group triterpenoidsRuss. J. Bioorg. Chem.26(3)192-200(2000)
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