Cicloprofen (Synonyms: (±)-Cicloprofen, α-Methylfluorene-2-acetic Acid, NSC 293916, SQ 20,824) |
Katalog-Nr.GC49082 |
An NSAID
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Cas No.: 36950-96-6
Sample solution is provided at 25 µL, 10mM.
Cicloprofen is a non-steroidal anti-inflammatory drug (NSAID).1,2 It inhibits histamine release induced by ragweed, A23187 , or concanavalin A in isolated human leukocytes when used at a concentration of 0.5 mM.1 Cicloprofen inhibits carrageenan-induced paw edema in rats (ED50 = 67 mg/kg).2
1.Hearn, T., and Wojnar, R.J.Characterization of augmentation of allergic and non-allergic histamine release by non-steroidal anti-inflammatory/analgesic agentsAgents Actions11(4)352-360(1981) 2.Stiller, E.T., Diassi, P.A., Gerschutz, D., et al.Synthesis and antiinflammatory activities of α-methylfluorene-2-acetic acid and related compoundsJ. Med. Chem.15(10)1029-1032(1972)
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