17(R)-Protectin D1 (Synonyms: Aspirin-triggered Protectin D1, 17-epi Neuroprotectin D1, 17(R)-Neuroprotectin D1, 17(R)-NPD1, 17(R)-PD1, 17-epi Protectin D1) |
Katalog-Nr.GC49178 |
An aspirin-triggered epimer of protectin D1
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Cas No.: 1365694-03-6
Sample solution is provided at 25 µL, 10mM.
17(R)-Protectin D1 is an aspirin-triggered epimer of the specialized pro-resolving mediator protectin D1 .1 It decreases leukotriene B4-induced transendothelial migration of human polymorphonuclear (PMN) neutrophils when used at concentrations ranging from 0.1 to 10 nM. 17(R)-Protectin D1 (0.01-10 ng) reduces the recruitment of neutrophils in a mouse model of TNF-α-induced peritonitis.
1.Serhan, C.N., Fredman, G., Yang, R., et al.Novel proresolving aspirin-triggered DHA pathwayChem. Biol.18(18)976-987(2011)
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