AZD 2716 |
| Katalog-Nr.GC49784 |
An sPLA2 inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1845753-81-2
Sample solution is provided at 25 µL, 10mM.
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AZD 2716 is an inhibitor of secretory phospholipase A2 (sPLA2; IC50s = 0.01, 0.04, and 0.4 µM for sPLA2-IIa, -V, and -X, respectively).1 It inhibits sPLA2 activity in atherosclerotic plaque homogenates isolated from patients with coronary artery disease (IC50 = 56 nM).
1.Giordanetto, F., Pettersen, D., Starke, I., et al.Discovery of AZD2716: A novel secreted phospholipase A2 (sPLA2) inhibitor for the treatment of coronary artery diseaseACS Med. Chem. Lett.7(10)884-889(2016)
Average Rating: 5 (Based on Reviews and 40 reference(s) in Google Scholar.)
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