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Bromfenac Sodium (Synonyms: AHR 10282B)

Katalog-Nr.GC13039

Bromfenac-Natrium ist ein potenter und oral aktiver Inhibitor von COX mit IC50-Werten von 5,56 und 7,45 nM fÜr COX-1 bzw. COX-2.

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Bromfenac Sodium Chemische Struktur

Cas No.: 91714-93-1

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10mM (in 1mL DMSO)
43,00 $
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50mg
48,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Protocol Chemical Properties Product Documents Related Products

Bromfenac (sodium hydrate) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity(1) Bromfenac (sodium hydrate) (1 mg/kg, i.v.) is metabolited into an unusual conjugate, bromfenac N-glucoside, in rats bile(2) Bromfenac (sodium hydrate) permeation was found to be 1.62-fold higher through ChS-CS-NPs

References:
[1]. Kirkman SK et al. Isolation and identification of bromfenac glucoside from rat bile. Drug Metab Dispos. 1998 Jul;26(7):720-3.
[2]. Abdullah TA et al. Chondroitin sulfate-chitosan nanoparticles for ocular delivery of bromfenac sodium: Improved permeation, retention, and penetration. Int J Pharm Investig. 2016 Apr-Jun;6(2):96-105.

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