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Cefcapene pivoxil hydrochloride hydrate

Katalog-Nr.GC39602 Copy One-Click Copy Product Info

Cefcapen-Pivoxil-Hydrochlorid-Hydrat ist ein Prodrug und ein oral aktives Cephalosporin der 3. Generation mit breitem antibakteriellem Wirkungsspektrum.

Products are for research use only. Not for human use. We do not sell to patients.

Cefcapene pivoxil hydrochloride hydrate Chemische Struktur

Cas No.: 147816-24-8

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25mg
42,00 $
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50mg
69,00 $
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100mg
102,00 $
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Sample solution is provided at 25 µL, 10mM.



Description of Cefcapene pivoxil hydrochloride hydrate

Cefcapene pivoxil hydrochloride hydrate is a prodrug and an orally active 3rd-generation cephalosporin with broad-spectrum of anti-bacterial activity[1]. Cefcapene pivoxil hydrochloride hydrate is used for the study of palmoplantar pustulosis (PPP) and other infectious diseases[2].

[1]. Murakami M, et al. Cefcapene Pivoxil Hydrochloride Is a Potentially New Treatment for Palmoplantar Pustulosis with Pustulotic Arthro-Osteitis.Dermatology. 2015;231(4):304-11. [2]. Kawada A, et al. Drug eruption induced by cefcapene pivoxil hydrochloride.Contact Dermatitis. 2001 Mar;44(3):197. [3]. Sekiya Y, et al. Comparative efficacies of different antibiotic treatments to eradicate nontypeable Haemophilus influenzae infection.BMC Infect Dis. 2008 Feb 7;8:15. [4]. Sekiya Y, et al. Comparative efficacies of different antibiotic treatments to eradicate nontypeable Haemophilus influenzae infection.BMC Infect Dis. 2008 Feb 7;8:15.

Chemical Properties of Cefcapene pivoxil hydrochloride hydrate

Cas No. 147816-24-8 SDF
Canonical SMILES [H]Cl.O=C1N([C@@]([H])([C@@H]1NC(/C(C2=CSC(N)=N2)=C\CC)=O)SC3)C(C(OCOC(C(C)(C)C)=O)=O)=C3COC(N)=O.O
Formula C23H32ClN5O9S2 M.Wt 622.11
Löslichkeit DMSO : 100mg/mL Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Cefcapene pivoxil hydrochloride hydrate

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.6074 mL 8.0372 mL 16.0743 mL
5 mM 321.5 μL 1.6074 mL 3.2149 mL
10 mM 160.7 μL 803.7 μL 1.6074 mL
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In vivo Formulation Calculator (Clear solution) of Cefcapene pivoxil hydrochloride hydrate

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 22 reference(s) in Google Scholar.)

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