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Chaetoglobosin A

Katalog-Nr.GC43234

Chaetoglobosin A, der Wirkstoff im Extrakt von Penicillium aquamarinium, ist ein Mitglied der Familie der Cytochalasane.

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Chaetoglobosin A Chemische Struktur

Cas No.: 50335-03-0

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1mg
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5mg
591,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Chaetoglobosin A, the active principle within the extract of Penicillium aquamarinium, is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration[1].

References:
[1]. Knudsen PB, et al. Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Leukemia. 2014 Jun;28(6):1289-98.

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