CID44216842 (Synonyms: Cdc42-IN-1) |
| Katalog-Nr.GC39810 |
CID44216842 (Cdc42-IN-1) ist ein potenter Cdc42-selektiver Inhibitor der Guaninnukleotidbindung. Die EC50-Werte fÜr Cdc42 WT- und Cdc42Q61L-Mutanten betragen 1,0 bzw. 1,2 μM im GTP-Bindungsassay. Die EC50-Werte fÜr Cdc42 WT- und Cdc42Q61L-Mutanten betragen 0,3 bzw. 0,5 μM im GDP-Bindungsassay. Verwendung als molekulare Sonde.
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Cas No.: 1222513-26-9
Sample solution is provided at 25 µL, 10mM.
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CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe[1].
[1]. Lin Hong, et al. Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe. J Biol Chem. 2013 Mar 22;288(12):8531-43.
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