D-3 |
| Katalog-Nr.GC50510 |
D-3, ein Phosphorpeptid, ist ein effizientes, einfaches und spezifisches iPSC-eliminierendes Mittel.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1967815-98-0
Sample solution is provided at 25 µL, 10mM.
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Selective PSC eliminating agent. Induces toxicity in cultured iPSCs and ESCs after 1 h of incubation, via an alkaline phosphatase-dependent mechanism. Only eliminates iPSCs in co-cultures with iPSC-derived neurons, cardiomyocytes or hepatocytes. Treated iPSC-derived cardiomyocytes transplanted into mice exhibit no residual teratoma formation.
Kuang et al (2017) Efficient, selective removal of human pluripotent stem cells via ecto-alkaline phosphatase-mediated aggregation of synthetic peptides. Cell Chem.Biol. 24 685 PMID:28529132
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
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