DBCO-PEG4-VC-PAB-DMEA-PNU-159682 |
| Katalog-Nr.GC63504 |
DBCO-PEG4-VC-PAB-DMEA-PNU-159682, ein Wirkstoff-Linker-Konjugat fÜrADC, besteht aus dem ADC-Linker DBCO-PEG4-VC-PAB und einem potenten ADC-Zytotoxin DMEA-PNU-159682. DMEA-PNU-159682 enthÄlt Metaboliten von Nemorubicin (MMDX) aus Lebermikrosomen und ADC-Zytotoxin PNU-159682.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2259318-56-2
Sample solution is provided at 25 µL, 10mM.
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DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker DBCO-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].
[1]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1
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