[Des-Arg9]-Bradykinin acetate |
| Katalog-Nr.GC33850 |
[Des-Arg9]-Bradykininacetat ist ein Bradykinin-B1-Rezeptoragonist, der SelektivitÄt fÜr B1- gegenÜber B2-Rezeptoren zeigt.
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![[Des-Arg9]-Bradykinin acetate Chemische Struktur](/media/struct/GC3/GC33850.png "[Des-Arg9]-Bradykinin acetate Chemische Struktur")
Cas No.: 23827-91-0
Sample solution is provided at 25 µL, 10mM.
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[Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors.
[Des-Arg9]-Bradykinin acetate is a Bradykinin(B1) receptor agonist. The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].
[1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.
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