Dofetilide N-oxide (Synonyms: CS 0019807, UK 116856) |
| Katalog-Nr.GC52052 |
Dofetilid-N-oxid (UK-116856) ist ein Metabolit von Dofetilid.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 144449-71-8
Sample solution is provided at 25 µL, 10mM.
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Dofetilide N-oxide is a metabolite of the antiarrhythmic agent dofetilide .1 It prolongs intracellular action potential duration in isolated guinea pig papillary muscle, as a measure of antiarrhythmic activity, less potently than dofetilide.
1.Walker, D.K., Alabaster, C.T., Congrave, G.S., et al.Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide. In vitro studies and correlation with in vivo dataDrug Metab. Dispos.24(4)447-455(1996)
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