EDANS |
| Katalog-Nr.GC61761 |
EDANS (1,5-EDANS) ist ein neuartiges und gequenchtes fluorogenes Substrat zum Testen retroviraler Protease durch Resonanzenergietransfer (RET).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 50402-56-7
Sample solution is provided at 25 µL, 10mM.
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EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET)[1].
The peptide sequence of EDANS is derived from a natural processing site for HIV-1 PR[1].Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that was linearly related to the extent of substrate hydrolysis[1].
[1]. E D Matayoshi, et al. Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer. Science. 1990 Feb 23;247(4945):954-8.
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