EGA |
| Katalog-Nr.GC43588 |
EGA ist ein selektiver Inhibitor von Endosomol-Transportwegen, die von mehreren Toxinen und Viren ausgenutzt werden.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 415687-81-9
Sample solution is provided at 25 µL, 10mM.
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EGA is an inhibitor of endosomal trafficking. It increases accumulation of fluorescently labeled EGF in early endosomes in HeLa cells when used at a concentration of 20 μM. EGA inhibits cell death induced by anthrax lethal toxin in RAW264.7 cells (IC50 = 1.7 μM) as well as by additional acid-dependent bacterial toxins, including diphtheria toxin, P. aeruginosa ExoA, and H. ducreyi cytolethal distending toxin (Hd-CDT), in various cell types. It also inhibits infection of Vero and HeLa cells by the low pH-dependent lymphocytic choriomeningitis (LCMV; Armstrong strain) and influenza A/WSN/33 viruses, respectively.
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
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