Asoprisnil (Synonyms: J867) |
| Katalog-Nr.GC35408 |
Asoprisnil (J867), ein selektiver Progesteronrezeptormodulator, zeigt gemischte Progesteronagonisten- und -antagonistenwirkungen auf verschiedene Progesteron-Zielgewebe bei Tieren und Menschen.
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Cas No.: 199396-76-4
Sample solution is provided at 25 µL, 10mM.
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Asoprisnil (J867), a selective progesterone receptor modulator, exhibits mixed progesterone agonist and antagonist effects on various progesterone targeted tissues in animal and human[1].
[1]. Stewart EA, et al. Safety and efficacy of the selective progesterone receptor modulator asoprisnil for heavy menstrual bleeding with uterine fibroids: pooled analysis of two 12-month, placebo-controlled, randomized trials. Hum Reprod. 2019 Apr 1;34(4):623-634. [2]. Wu XL, et al. Postcoital administration of asoprisnil inhibited embryo implantation and disturbed ultrastructure of endometrium in implantation window in mice. J Huazhong Univ Sci Technolog Med Sci. 2013 Apr;33(2):277-283.
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