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PCTR3 (Synonyms: Protein Conjugates in Tissue Regeneration 3)

Katalog-Nr.GC44581 Copy One-Click Copy Product Info

Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid.

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PCTR3 Chemische Struktur

Cas No.: 1810710-69-0

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10μg
283,00 $
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25μg
673,00 $
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50μg
1.204,00 $
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100μg
2.125,00 $
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Sample solution is provided at 25 µL, 10mM.



Description of PCTR3

Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutathione S-transferase and to PCTR2 and PCTR3 via peptidases. PCTR3 is found in infected mouse spleens and resolving exudate as well as isolated human spleen and septic plasma. It is also found in both M1 and M2 macrophages differentiated from isolated human monocytes.

Chemical Properties of PCTR3

Cas No. 1810710-69-0 SDF
Überlieferungen Protein Conjugates in Tissue Regeneration 3
Canonical SMILES CC/C=C\C[C@H](O)[C@H](SC[C@@H](C(O)=O)N)/C=C/C=C/C=C\C/C=C\C/C=C\CCC(O)=O
Formula C25H37NO5S M.Wt 463.6
Löslichkeit DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 1 mg/ml,Ethanol:H20 (95:5): 2 mg/ml,PBS (pH 7.2): 0.1 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of PCTR3

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.157 mL 10.7852 mL 21.5703 mL
5 mM 431.4 μL 2.157 mL 4.3141 mL
10 mM 215.7 μL 1.0785 mL 2.157 mL
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In vivo Formulation Calculator (Clear solution) of PCTR3

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 7 reference(s) in Google Scholar.)

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