Jagged-1 188-204 |
| Katalog-Nr.GC36362 |
Jagged-1 188-204 ist ein Fragment des Jagged-1 (JAG-1)-Proteins mit Notch-Agonist-Aktivität. JAG-1 ist ein Notch-Ligand, der in kultivierten und primären Zellen des multiplen Myeloms (MM) stark exprimiert wird. JAG-1 induziert die Reifung von Monozyten-abgeleiteten menschlichen dendritischen Zellen.
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Cas No.: 219127-21-6
Sample solution is provided at 25 µL, 10mM.
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Jagged-1 (188-204) is a fragment of the Jagged-1 (JAG-1) protein. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells[1][2].
[1]. Jundt F, et al. Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells. Blood. 2004 May 1;103(9):3511-5. [2]. Weijzen S, et al. The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendriticcells. J Immunol. 2002 Oct 15;169(8):4273-8.
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