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KT185

Katalog-Nr.GC36401

KT185 ist ein oral bioverfÜgbarer, in das Gehirn eindringender und selektiver ABHD6-Inhibitor mit einem IC50-Wert von 0,21 nM in Neuro2A-Zellen.

Products are for research use only. Not for human use. We do not sell to patients.

KT185 Chemische Struktur

Cas No.: 1472640-86-0

Größe Preis Lagerbestand Menge
5mg
185,00 $
Auf Lager
10mg
324,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells[1]. IC50: ABHD6 (0.21 nM in Neuro2A cells)[1].

[1]. Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6). J Med Chem. 2013 Nov 14;56(21):8270-9.

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Average Rating: 5 ★★★★★ (Based on Reviews and 36 reference(s) in Google Scholar.)

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