MC-Val-Cit-PAB-rifabutin |
| Katalog-Nr.GC36574 |
MC-Val-Cit-PAB-Rifabutin ist ein Wirkstoff-Linker-Konjugat fÜr ADC mit starker AntitumoraktivitÄt unter Verwendung von Rifabutin (einem DNA-abhÄngigen RNA-Polymerase-Inhibitor), das Über den ADC-Linker MC-Val-Cit-PAB verknÜpft ist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2055900-34-8
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
MC-Val-Cit-PAB-rifabutin has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-rifabutin is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].
[1]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *