N4-Acetylcytidine triphosphate sodium (Synonyms: ac4CTP sodium) |
| Katalog-Nr.GC36678 |
N4-Acetylcytidintriphosphat-Natrium wird effizient als Substrat in der T7-Polymerase-katalysierten In-vitro-Transkription verwendet und kann in mehrere Templates eingebaut werden.
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Cas No.: 2803886-33-9
Sample solution is provided at 25 µL, 10mM.
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N4-Acetylcytidine triphosphate sodium is a endogenous nucleoside metabolite from the degradation of tRNA, primes and activates NLRP3 inflammation by inducing HMGB1 expression[1]. NLRP3 Human Endogenous Metabolite
N4-Acetylcytidine (0.3? mM or 1.0? mM) upregulates NF-κB and NLRP3 expression BV2 microglia, and this calls for HMGB1 expression and release[1].
[1]. Duan J, et al. N4-acetylcytidine is required for sustained NLRP3 inflammasome activation via HMGB1 pathway in microglia. Cell Signal. 2019 Jun;58:44-52.
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