N-Boc-Phe-Leu-Phe-Leu-Phe (Synonyms: Boc-FLFLF) |
| Katalog-Nr.GC36706 |
N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) ist ein Antagonist des Formylpeptidrezeptors 1 (FPR1), der die Schmerzwirkung verstÄrkt und die antinozizeptive AktivitÄt von Annexin hemmt.
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Cas No.: 148182-34-7
Sample solution is provided at 25 µL, 10mM.
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N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin[1][2]. FPR1[1]
[1]. Schepetkin IA, et al. Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones. Biochem Pharmacol. 2014 Dec 15;92(4):627-41. [2]. Pei L, et al. Annexin 1 exerts anti-nociceptive effects after peripheral inflammatory pain through formyl-peptide-receptor-like 1 in rat dorsal root ganglion. Br J Anaesth. 2011 Dec;107(6):948-58.
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