Quetiapine sulfoxide |
| Katalog-Nr.GC37056 |
Quetiapinsulfoxid (Quetiapin-S-oxid) ist ein Hauptmetabolit von Quetiapinem.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 329216-63-9
Sample solution is provided at 25 µL, 10mM.
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Quetiapine sulfoxide (Quetiapine S-oxide) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1].
The Cmax value (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUClast value is estimated for Quetiapine sulfoxide (1,286±458 ng•h/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing[1].
[1]. Remmerie B, et al. Comparison of Capillary and Venous Drug Concentrations After Administration of a Single Dose of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole. Clin Pharmacol Drug Dev. 2016 Nov;5(6):528-537.
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