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VCP-Eribulin

Katalog-Nr.GC37892

VCP-Eribulin besteht aus den ADCs Linker (VCP) und Eribulin. Eribulin ist ein mechanistisch einzigartiger Mikrotubuli-Inhibitor fÜr Krebs. VCP-Eribulin ist ein auf Eribulin basierendes Medikament fÜr AntikÖrperkonjugate.

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VCP-Eribulin Chemische Struktur

Cas No.: 2130869-17-7

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

VCP-Eribulin consists the ADCs linker (VCP) and Eribulin[1]. Eribulin is a mechanistically unique microtubule inhibitor for cancer[2]. VCP-Eribulin is an Eribulin-based drug for antibody conjugates[1].

[1]. Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1. [2]. Towle MJ, et al. Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions. Cancer Res. 2011 Jan 15;71(2):496-505.

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