Picrotin |
Katalog-Nr.GC38219 |
Picrotin ist ein Wirkstoff, der auch zu der Zusammensetzung von Picrotoxin (einem Antagonisten von GABAA-Rezeptoren (GABAARs) und Glycinrezeptoren (GlyRs)) gehÖrt.
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Cas No.: 21416-53-5
Sample solution is provided at 25 µL, 10mM.
Picrotin is an inhibitor of glycine receptors (GlyRs) which blocks α2 GlyR, α1 GlyR and α3 GlyR[1][2].
[1]. Li P, et al. Gating effects on picrotin block of glycine receptors. Neuroreport. 2012 Dec 5;23(17):1017-20. [2]. Yang Z, et al. A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore. J Neurochem. 2007 Oct;103(2):580-9.
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