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GSK 2250665A

Katalog-Nr.GC50156

GSK 2250665A (Verbindung 13) ist ein selektiver Itk-Inhibitor mit einem pKi von 9,2.

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GSK 2250665A Chemische Struktur

Cas No.: 1246030-96-5

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5 mg
332,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Itk inhibitor (pKi = 9.2). Exhibits selectivity for Itk over Aurora B kinase and Btk (pIC50 values are 6.4 and 6.5, respectively) and a panel of other kinases. Inhibits IFNγ production in PBMCs.

Alder et al (2013) Identification of a novel and selective series of Itk inhibitors via a template-hopping strategy. ACS Med.Chem.Lett. 12 948 PMID:24900590

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Average Rating: 5 ★★★★★ (Based on Reviews and 26 reference(s) in Google Scholar.)

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