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JNJ DGAT2-A

Katalog-Nr.GC50285

JNJ DGAT2-A ist ein selektiver Diacylglycerolacyltransferase 2 (DGAT2)-Inhibitor mit einem IC50-Wert von 0,14 μM in humanen DGAT2-exprimierenden Sf9-Insektenzellmembranen.

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JNJ DGAT2-A Chemische Struktur

Cas No.: 1962931-71-0

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1mg
74,00 $
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5mg
162,00 $
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10mg
284,00 $
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25mg
567,00 $
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50mg
891,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

DGAT2 inhibitor (IC50 = 140 nM). Exhibits >70-fold selectivity for DGAT2 over DGAT1 and MGAT2.

Qi et al (2012) The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2 J.Lipid Res. 53 1106 PMID:22493088 |Irshad et al (2017) Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes. J.Lipid Res. 58 15 PMID:27836993

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