Lei-Dab7 TFA |
| Katalog-Nr.GC66240 |
Lei-Dab7 TFA ist ein selektiver KCa2.2 (SK2)-Kanalblocker mit hoher AffinitÄt (Kd = 3,8 nM). Lei-Dab7 TFA zeigt eine >200-fache SelektivitÄt fÜr KCa2.2 gegenÜber KCa2.1, KCa2.3, KCa3.1, Kv und Kir2.1. Lei-Dab7 TFA erhÖht die Theta-Burst-Antworten und erhÖht LTP in Hippocampus-Schnitten von Ratten in vitro.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Lei-Dab7 TFA is a high affinity, selective KCa2.2 (SK2) channel blocker (Kd=3.8 nM). Lei-Dab7 TFA exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, Kv and Kir2.1. Lei-Dab7 TFA increases theta-burst responses and increases LTP in rat hippocampal slices in vitro.
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