Malachite Green (chloride) (Synonyms: Basic Green 4, C.I. 4200, C.I. 42000) |
Katalog-Nr.GC52358
One-Click Copy Product Info
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A triphenylmethane dye
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 569-64-2
Sample solution is provided at 25 µL, 10mM.
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Malachite green is a triphenylmethane dye.1 It inhibits the proliferation of HEp-2 human larynx cells (IC50 = 2.06 µM). Malachite green is cytotoxic to HEp-2 cells and Caco-2 human colorectal adenocarcinoma cells (IC50s = 2.03 and 13.8 µM, respectively). It reduces fungal infection in, and increases hatching rates of, rainbow trout eggs when used at a concentration of 2 µg/ml for 60 minutes twice a week.2 Malachite green has been used as a biochemical indicator dye for titrations, pH indicators, and counterstains in histology applications.3,4,5 Formulations containing malachite green have been used in the textile and pigment industries as dyes.
1.Stammati, A., Nebbia, C., De Angelis, I., et al.Effects of malachite green (MG) and its major metabolite, leucomalachite green (LMG), in two human cell linesToxicol. In Vitro19(7)853-858(2005) 2.Kitancharoen, N., Yamamoto, A., and Hatai, K.Effects of sodium chloride, hydrogen peroxide and malachite green on fungal infection in rainbow trout eggsBiocontrol Sci.3(2)113-115(1998) 3.Tuthill, S.M., Kolling, O.W., and Roberts, K.H.Photometric and visual titration of certain alkaloids in glacial acetic acid using malachite green as indicatorAnal. Chem.32(12)1678-1681(1960) 4.Decnop-Weever, L.G., and Kraak, J.C.Determination of sulphite in wines by gas-diffusion flow injection analysis utilizing spectrophotometric pH-detectionAnalytica Chimica Acta337125-131(1997) 5.Dutton, R.J., Bitton, G., and Koopman, B.Malachite green-INT (MINT) method for determining active bacteria in sewageAppl. Environ. Microbiol.46(6)1263-1267(1983)
| Cas No. | 569-64-2 | SDF | |
| Überlieferungen | Basic Green 4, C.I. 4200, C.I. 42000 | ||
| Canonical SMILES | CN(C)C(C=C1)=CC=C1/C(C2=CC=CC=C2)=C3C=C/C(C=C/3)=[N+](C)/C.[Cl-] | ||
| Formula | C23H25N2Cl | M.Wt | 364.9 |
| Löslichkeit | DMF: 1 mg/ml,DMSO: 1 mg/ml,Ethanol: 0.5 mg/ml,PBS (pH 7.2): 0.25 mg/ml | Storage | -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 2.7405 mL | 13.7024 mL | 27.4048 mL |
| 5 mM | 548.1 μL | 2.7405 mL | 5.481 mL |
| 10 mM | 274 μL | 1.3702 mL | 2.7405 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >96.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)