MCL-1/BCL-2-IN-3 |
Katalog-Nr.GC38928 |
MCL-1/BCL-2-IN-3 (Verbindung 2) ist ein potenter und selektiver dualer Mcl-1- und Bcl-2-Inhibitor mit IC50-Werten von 5,95 bzw. 4,78 μM.
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Cas No.: 2163793-55-1
Sample solution is provided at 25 µL, 10mM.
MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectively[1].
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
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