Myricetin 3-galactoside (Synonyms: Myricetin 3-O-β-galactopyranoside, Myricetin 3-O-β-D-galactopyranoside, Myricetin 3-O-galactoside, Myricetin 3-β-D-galactoside) |
Katalog-Nr.GC52049 |
Myricetin 3-Galactosid hemmt die AktivitÄt der Xanthinoxidase (XO), die Lipidperoxidation und fÄngt freie Radikale ab.
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Cas No.: 15648-86-9
Sample solution is provided at 25 µL, 10mM.
Myricetin 3-galactoside is a flavonoid that has been found in M. communis and has diverse biological activities.1,2 It inhibits xanthine oxidase in a cell-free assay when used at a concentration of 100 µg/ml.1 Myricetin 3-galactoside is cytotoxic to K562 cells (IC50 = 220 µg/ml) and inhibits hydrogen peroxide-induced malondialdehyde (MDA) formation in the same cells when used at concentrations of 110, 220, and 440 µg/ml.1 In vivo, myricetin 3-galactoside (0.26 and 0.78 mg/kg) reduces carrageenan-induced paw edema in wild-type but not nos2-/- mice.2 It also reduces formalin-induced paw licking in mice.
1.Hayder, N., Bouhlel, I., Skandrani, I., et al.In vitro antioxidant and antigenotoxic potentials of myricetin-3-o-galactoside and myricetin-3-o-rhamnoside from Myrtus communis: modulation of expression of genes involved in cell defence system using cDNA microarrayToxicol. In Vitro22(3)567-581(2008) 2.de Oliveira Azevedo, A., Campos, J.J., de Souza, G.G., et al.Antinociceptive and anti-inflammatory effects of myricetin 3-O-β-galactoside isolated from Davilla elliptica: Involvement of the nitrergic systemJ. Nat. Med.69(4)487-493(2015)
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