N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Synonyms: DANA) |
| Katalog-Nr.GC44298 |
N-Acetyl-2,3-dehydro-2-desoxyneuraminsÄure (Neu5Ac2en) ist ein potenter Neuraminidase (Sialidase)-Hemmer.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 24967-27-9
Sample solution is provided at 25 µL, 10mM.
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N-acetyl-2,3-dehydro-2-Deoxyneuraminic acid (DANA) is an inhibitor of human neuriminidases (sialidases) NEU1-4 (IC50s = 143, 43, 61, and 74 μM, respectively). In vivo, DANA (30 μL of a 5 mM solution) reduces latency to first seizure and increases seizure duration in a rat model of potassium-induced seizures.
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