N-trans-Feruloyltyramine (Synonyms: Alfrutamide, (E)-Feruloyltyramine, Moupinamide) |
| Katalog-Nr.GC40686 |
N-trans-Feruloyltyramin (N-Feruloyltyramin), ein Alkaloid aus Piper Nigru, ist ein Inhibitor von COX1 und COX2 mit potenziellen antioxidativen Eigenschaften.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 66648-43-9
Sample solution is provided at 25 µL, 10mM.
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N-trans-Feruloyltyramine is a phenolic amide originally isolated from S. melongena that has diverse biological activities, including anti-inflammatory, antioxidative, and antiproliferative properties. It decreases nitric oxide (NO) production (IC50 = 17.36 µM) and inducible NO synthase (iNOS) activity and increases NO scavenging without inducing cytotoxicity in LPS-stimulated BV-2 cells. It also scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in TLC autographic and spectrophotometric assays. N-trans-Feruloyltyramine inhibits proliferation of HeLa and L929 cells by 72.2 and 22%, respectively, when used at a concentration of 30 µg/ml.
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