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NH2-PEG6-CH2CH2COOH

Katalog-Nr.GC62171

NH2-PEG6-CH2CH2COOH ist ein spaltbarer PEG-ADC-Linker mit 6 Einheiten, der bei der Synthese von AntikÖrper-Wirkstoff-Konjugaten (ADCs) verwendet wird. NH2-PEG6-CH2CH2COOH ist auch ein PEG-basierter PROTAC-Linker, der bei der Synthese von PROTACs verwendet werden kann.

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NH2-PEG6-CH2CH2COOH Chemische Struktur

Cas No.: 905954-28-1

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100 mg
90,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

NH2-PEG6-CH2CH2COOH is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[1]. Jaume Pons, et al. Engineered polypeptide conjugates and methods for making thereof using transglutaminase. US20130230543A1.

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