NH2-PEG6-CH2CH2COOH |
Katalog-Nr.GC62171 |
NH2-PEG6-CH2CH2COOH ist ein spaltbarer PEG-ADC-Linker mit 6 Einheiten, der bei der Synthese von AntikÖrper-Wirkstoff-Konjugaten (ADCs) verwendet wird. NH2-PEG6-CH2CH2COOH ist auch ein PEG-basierter PROTAC-Linker, der bei der Synthese von PROTACs verwendet werden kann.
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Cas No.: 905954-28-1
Sample solution is provided at 25 µL, 10mM.
NH2-PEG6-CH2CH2COOH is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
[1]. Jaume Pons, et al. Engineered polypeptide conjugates and methods for making thereof using transglutaminase. US20130230543A1.
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