Nifedipine-d6 |
| Katalog-Nr.GC40207 |
Nifedipin D6 (BAY-a-1040 D6) ist mit Deuterium markiertes Nifedipin, und Nifedipin ist ein potenter Calciumkanalblocker.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1188266-14-9
Sample solution is provided at 25 µL, 10mM.
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Nifedipine-d6 is intended for use as an internal standard for the quantification of nifedipine by GC- or LC-MS. Nifedipine is a dihydropyridine L-type calcium channel blocker that reduces the amplitude of spontaneous contractions in isolated rabbit ileum when used at a concentration of 1 μM. Nifedipine (1 μM) reduces TGF-β-induced calcium oscillations in human fibroblasts and prevents impairment of lung function in a mouse model of pulmonary fibrosis induced by bleomycin when administered at a dose of 10 mg/kg per day. It also reduces increases in mean arterial blood pressure induced by angiotensin II in spontaneously hypertensive rats when administered at a dose of 10 μg/kg. Formulations containing nifedipine have been used in the treatment of hypertension and angina.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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