O-Nornuciferine |
| Katalog-Nr.GC63129 |
O-Nornuciferin, ein Alkaloid vom Aporphin-Typ aus LotusblÄttern, ist ein potenter hERG-Kanal-Inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 3153-55-7
Sample solution is provided at 25 µL, 10mM.
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O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor[1].
O-Nornuciferine has an IC50 of 7.91 μM in vitro hERG blockages measured in HEK293 cells[1]. O-Nornuciferine (100 μM) has 47% hERG channel inhibition in Xenopus oocytes by lotus alkaloids[1].
[1]. Ulrike Grienke, et al. Human Ether-À-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids From Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements. J Agric Food Chem. 2015 Jun 17;63(23):5634-9.
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