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Otamixaban hydrochloride

Katalog-Nr.GC71580 Copy One-Click Copy Product Info

Otamixaban hydrochloride ist ein potenter, selektiver, schnell wirkender, kompetitiver und reversibler fXa-Hemmer (Ki=0,5 nM), der sowohl freies als auch prothrombinase-gebundenes fXa wirksam hemmt.

Products are for research use only. Not for human use. We do not sell to patients.

Otamixaban hydrochloride Chemische Struktur

Cas No.: 409081-12-5

Größe Preis Lagerbestand Menge
5 mg
135,00 $
Auf Lager
10 mg
212,00 $
Auf Lager
25 mg
423,00 $
Auf Lager
50 mg
675,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.



Description of Otamixaban hydrochloride

Otamixaban (FXV673) is a potent, selective, rapid-acting, competitive, and reversible fXa inhibitor (Ki=0.5 nM) that effectively inhibits both free and prothrombinase-bound fXa.

References:
[1]. Eikelboom JW, Weitz JI.Otamixaban in acute coronary syndromes.Lancet. 2009 Sep 5;374(9692):762-4. Epub 2009 Aug 28.

Chemical Properties of Otamixaban hydrochloride

Cas No. 409081-12-5 SDF
Formula C25H27ClN4O4 M.Wt 482.96
Löslichkeit Storage 4°C, sealed storage, away from moisture
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Otamixaban hydrochloride

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.0706 mL 10.3528 mL 20.7056 mL
5 mM 414.1 μL 2.0706 mL 4.1411 mL
10 mM 207.1 μL 1.0353 mL 2.0706 mL
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In vivo Formulation Calculator (Clear solution) of Otamixaban hydrochloride

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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