Penicillide (Synonyms: Vermixocin A) |
| Katalog-Nr.GC40622 |
Penicillid (Vermixocin A), isoliert aus auf Reis kultiviertem Talaromyces derxii, zeigt eine hemmende AktivitÄt gegen Acyl-CoA:Cholesterin-Acyltransferase (ACAT).
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Cas No.: 55303-92-9
Sample solution is provided at 25 µL, 10mM.
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Penicillide is a fungal metabolite originally isolated from Penicillium that has diverse biological activities. It is an inhibitor of calpain 2/m-calpain (IC50 = 7.1 µM) and acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 22.9 µM). It is also an antagonist of oxytocin receptors (IC50 = 67 µM). Penicillide inhibits RNA synthesis in P388 murine leukemia cells.
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