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Pomalidomide 4'-PEG3-acid

Katalog-Nr.GC50545

Pomalidomide 4'-PEG3-SÄure ist ein synthetisiertes E3-Ligase-Ligand-Linker-Konjugat, das den auf Thalidomid basierenden Cereblon-Liganden und den 3-Einheiten-PEG-Linker enthÄlt, die in der PROTAC-Technologie verwendet werden.

Products are for research use only. Not for human use. We do not sell to patients.

Pomalidomide 4'-PEG3-acid Chemische Struktur

Cas No.: 2138440-82-9

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25 mg
182,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Pomalidomide - linker 2 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Remillard et al (2017) Degradation of the BAF complex factor BRD9 by heterobifunctional ligands. Angew.Chem.Int.Ed.Engl. 56 5738 PMID:28418626

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